News & Highlights
Ravi Ramasamy, PhD was awarded a shared instrumentation grant from the National Institutes of Health for the acquisition of Seahorse system. This state of the art automated system will be used to assess cellular respiration, mitochondrial properties, and glycolysis in real time. Seahorse system will be placed within the Research Support Core at NYULMC.
On May 7, 2013, the Department of Medicine held its 12th Annual Research Day. Several members of the Diabetes Research Program participated in this event.<<more>>
The Diabetes Research Program and NYU's Initiative in Data Science and Statistics were awarded a research grant from Independence Blue Cross. The goal of this collaboration is twofold; detect undiagnosed diabetes cases and predict potential cases of the disease. <<more>>
Ann Marie Schmidt, MD and Ravi Ramasamy, PhD were awarded a grant from the NYU Abu Dhabi Institute. In collaboration with the NYU Abu Dhabi Public Health Research Institute, the project will examine the growing obesity and diabetes epidemic in Abu Dhabi.
Ravi Ramasamy, PhD and Gabrielle Gold-von Simson, MD were awarded a multi-PI R25 grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIH). The grant titled “A New Era of Targeted Drug Discovery and the Path of Development” will enable NYU School of Medicine to offer a modern and innovative NIDDK-relevant course series with a multidisciplinary curriculum. This series of courses and seminars is intended to delineate how the very nature of drug development impinges upon the scientific understanding of a drug and its target(s) from its genesis at the bench through post-marketing experience and back again. The ultimate goal of this funded program is to stimulate new investigators across diverse disciplines to the field of drug development with a focus on diabetes, diabetic complications and obesity.
Ann Marie Schmidt, MD , Ravi Ramasamy, PhD and Shi Fang Yan, MD received notice that the competitive renewal of their Program Project grant on RAGE and mechanisms of vascular dysfunction has been funded by the NHLBI. This accomplishment of the Diabetes Research Program was featured in NYULMC2 .
Mariane Abdillahi , a graduate research assistant, successfully defended her PhD thesis at Columbia University .
Karen O’Shea, PhD , a postdoctoral fellow in Dr. Ravi Ramasamy ’s lab, was awarded an F32 Postdoctoral Fellowship award by the NIH.
Ann Marie Schmidt, MD , Ravi Ramasamy, PhD and Shi Fang Yan, MD were awarded a Multi-Project grant from the JDRF to screen for novel inhibitors of RAGE-mDia1 interaction and to dissect the role of mDia1 in diabetic complications.
In November 2011 we published the results of our collaborative studies with Columbia University and Memorial Sloan Kettering on RAGE and massive liver resection. Our results crystallize the concept that RAGE is not primarily involved in innate immune responses; rather, RAGE perpetuates inflammatory signals that lead to excessive cellular and tissue damage. Our findings suggest that blockade of RAGE may be an effective strategy for curtailing adverse inflammation in extensive liver damage. <<more>>